Web19 jul. 2024 · Below, we’ll cover 10 little-known but useful facts about Topamax. 1. Topamax uses can vary. Topamax is FDA-approved for migraine prevention and epilepsy … WebAdverse reactions include decreased appetite, vomiting, insomnia, nausea, dizziness, somnolence, and headache. Many patients report increased alertness with the drug. Two rare but very serious effects include aplastic anemia and serious liver damage. The risk of aplastic anemia is between 1:3,600 and 1:5,000, of which 30% of cases are fatal.
Topiramate C12H21NO8S - PubChem
Topiramate itself is a weak inhibitor of CYP2C19 and induces CYP3A4; a decrease in plasma levels of estrogens and digoxin has been noted during topiramate therapy. This can reduce the effectiveness of oral contraceptives (birth control pills); use of alternative birth control methods is recommended. [49] Meer weergeven Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. It has also been used in alcohol dependence. For epilepsy this includes treatment for Meer weergeven People taking topiramate should be aware of the following risks: • Avoid activities requiring mental alertness and coordination until drug effects are realized. • Topiramate may impair heat regulation, especially in children. Use caution with … Meer weergeven Topiramate has many drug-drug interactions. Some of the most common are listed below: • As … Meer weergeven Topiramate was discovered in 1979 by Bruce E. Maryanoff and Joseph F. Gardocki during their research work at McNeil Pharmaceuticals. Topiramate was first sold in 1996. Mylan Pharmaceuticals was granted final approval by the FDA for the sale of … Meer weergeven Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant. In children, it is indicated for … Meer weergeven Symptoms of acute and acute on chronic exposure to topiramate range from asymptomatic to status epilepticus, including in patients with no seizure history. In … Meer weergeven The topiramate molecule is a sulfamate modified sugar, more specifically, fructose diacetonide, an unusual chemical structure for a pharmaceutical. Topiramate is quickly absorbed after oral use. It has a half life of 21 hours and a steady state … Meer weergeven Web20 okt. 2016 · Generic Name Carisbamate DrugBank Accession Number DB12338 Background Carisbamate has been investigated in Alcohol Abuse, Substance Abuse, and Alcohol Dependence. Type Small Molecule Groups Investigational Structure 3D Download Similar Structures Weight Average: 215.63 Monoisotopic: 215.0349209 Chemical … f2 mother\u0027s
A Step-by-Step Guide to Prescribing Weight Loss Medications …
Web4 nov. 2002 · Wegens tandvleeshypertrofie werd de fenytoïne vervangen door topiramaat 50 mg/dag. Tijdens behandeling met dit anticonvulsivum nam de aanvalsfrequentie toe … Web27 mrt. 2024 · Topiramate is an anticonvulsant lowering the seizure threshold stabilizing membrane by acting on high-voltage-activated calcium channels and voltage-gated sodium channels and its augmenting effect on GABA-A receptors. Topiramate is also a weak carbonic anhydrase inhibitor, and it also antagonizes glutamate receptors. WebValproic acid (Depa) MOA. Traditional AED. Suppresses sodium, suppresses calcium, inhibits GABA. Valproic acid (Depa) uses-seizures-bipolar-migraine. Valproic acid (Depa) adverse-hepatotoxicity-teratogenic effects. Valproic acid (Depa) interactions. phenytoin, topiramate, meropenem, phenobarbital. Ethosuximide (Zarontin) uses. absence seizures ... f2 mountain\u0027s